Title : Overexpression of miR-215-3p sensitizes colorectal cancer to 5-fluorouracil induced apoptosis through regulating CXCR1.

Pub. Date : 2018 Nov

PMID : 30468467






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Overexpression of miR-215-3p sensitizes colorectal cancer to 5-fluorouracil induced apoptosis through regulating CXCR1. Fluorouracil microRNA 215 Homo sapiens
2 RESULTS: miR-215-3p was down-expressed in the 5-FU resistant cell compared to the parent cell. Fluorouracil microRNA 215 Homo sapiens
3 Furthermore, miR-215-3p accelerated the apoptosis of colorectal cancer cell which was treated with 5-Fu. Fluorouracil microRNA 215 Homo sapiens
4 Mechanically, miR-215-3p regulated the level of endogenous CXCR1 in HCT116 cell and alternation of CXCR1 affected the 5-Fu sensibility mediated by miR-215-3p. Fluorouracil microRNA 215 Homo sapiens
5 Mechanically, miR-215-3p regulated the level of endogenous CXCR1 in HCT116 cell and alternation of CXCR1 affected the 5-Fu sensibility mediated by miR-215-3p. Fluorouracil microRNA 215 Homo sapiens