Title : Ryanodine Receptor-Mediated Calcium Release Has a Key Role in Hippocampal LTD Induction.

Pub. Date : 2018

PMID : 30459562






1 Functional Relationships(s)
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1 Pre-incubation of slices with ryanodine (1 muM, 1 h) or caffeine (1 mM, 30 min) to promote RyR-mediated Ca2+ release facilitated LTD induction by low frequency stimulation (LFS), but did not affect the amplitude of synaptic transmission, the profiles of field excitatory postsynaptic potentials (fEPSP) or the paired-pulse (PP) responses. Caffeine ryanodine receptor 2 Rattus norvegicus