Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase.

Pub. Date : 2019 Mar 15

PMID : 30458057






2 Functional Relationships(s)
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1 Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase. tabun acetylcholinesterase (Cartwright blood group) Homo sapiens
2 We identified several oximes with significantly improved in vitro reactivating potential for tabun-inhibited human AChE, and in vivo antidotal efficacies in tabun-exposed mice. tabun acetylcholinesterase (Cartwright blood group) Homo sapiens