Title : Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes.

Pub. Date : 2018 Nov

PMID : 30455079






2 Functional Relationships(s)
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Protein Name
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1 IL-2 induction of p-STAT1 and p-STAT3 phosphorylation was significantly decreased after calcitriol or EB1089 treatment. seocalcitol signal transducer and activator of transcription 3 Homo sapiens
2 We treated NK-LGLL patient PBMCs with calcitriol or EB1089 and found decreased p-STAT1 and p-STAT3 while VDR increased, which matched the NKL cell line data. seocalcitol signal transducer and activator of transcription 3 Homo sapiens