Title : Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae.

Pub. Date : 2018

PMID : 30450126






1 Functional Relationships(s)
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1 Interestingly, overexpressing OLE1 resulted in the increased levels of oleic acid (18:1n-9) and an increase in the unsaturation index of fatty acids in the plasma membrane, resulting in higher tolerance to acetic, formic and levulinic acid, while this change was found to be detrimental to cells exposed to lipophilic cinnamic acid. Oleic Acid stearoyl-CoA 9-desaturase Saccharomyces cerevisiae S288C