Pub. Date : 2019 Feb 5
PMID : 30418757
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here we show that, upon incorporation into short ssDNAs, the cytidine nucleoside analogue 2"-deoxyzebularine (dZ) becomes capable of inhibiting the catalytic activity of selected APOBEC variants derived from APOBEC3A, APOBEC3B, and APOBEC3G, supporting a mechanism in which ssDNA delivers dZ to the active site. | 2'-deoxyzebularine | apolipoprotein B mRNA editing enzyme catalytic subunit 3B | Homo sapiens |
2 | Here we show that, upon incorporation into short ssDNAs, the cytidine nucleoside analogue 2"-deoxyzebularine (dZ) becomes capable of inhibiting the catalytic activity of selected APOBEC variants derived from APOBEC3A, APOBEC3B, and APOBEC3G, supporting a mechanism in which ssDNA delivers dZ to the active site. | 2'-deoxyzebularine | apolipoprotein B mRNA editing enzyme catalytic subunit 3B | Homo sapiens |