Pub. Date : 2019 Jan 5
PMID : 30412729
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ketamine-induced hypothermia was significantly attenuated by pretreatment with the selective 5-HT2C receptor agonist WAY-163909 but not by pretreatment with the mixed 5-HT2A/2C receptor agonist 2,5-dimethoxy-4-iodoamphetamine (DOI). | Ketamine | 5-hydroxytryptamine (serotonin) receptor 2C | Mus musculus |
| 2 | Moreover, the blockade of ketamine-induced hypothermia by WAY-163909 was reversed by pretreatment with the selective 5-HT2C receptor antagonist SB-242084. | Ketamine | 5-hydroxytryptamine (serotonin) receptor 2C | Mus musculus |
| 3 | These findings demonstrate that stimulation of 5-HT2C receptors can reduce AIH, at least for ketamine-induced hypothermia. | Ketamine | 5-hydroxytryptamine (serotonin) receptor 2C | Mus musculus |