Pub. Date : 1987 Sep
PMID : 3040807
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Studies of the mechanism of suppression revealed (a) a classical opioid receptor is involved (suppression was antagonized by naloxone and was specific for the NH2 terminus of beta-END), (b) monocytes are the primary target cell for opioids (monocyte-depleted lymphocyte preparations showed little suppression), and (c) reactive oxygen intermediates (ROI) and prostaglandin E2 are important mediators (scavengers of ROI and indomethacin eliminated the suppression). | Indomethacin | proopiomelanocortin | Homo sapiens |