Title : Absence of the sulfate transporter SAT-1 has no impact on oxalate handling by mouse intestine and does not cause hyperoxaluria or hyperoxalemia.

Pub. Date : 2019 Jan 1

PMID : 30383413






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The anion exchanger SAT-1 [sulfate anion transporter 1 (Slc26a1)] is considered an important regulator of oxalate and sulfate homeostasis, but the mechanistic basis of these critical roles remain undetermined. Oxalates spermidine/spermine N1-acetyl transferase 1 Mus musculus
2 NEW & NOTEWORTHY SAT-1 is a membrane-bound transport protein expressed in the intestine, liver, and kidney, where it is widely considered essential for the excretion of oxalate, a potentially toxic waste metabolite. Oxalates spermidine/spermine N1-acetyl transferase 1 Mus musculus
3 Previously, calcium oxalate kidney stone formation by the SAT-1-knockout mouse generated the hypothesis that SAT-1 has a major role in oxalate excretion via the intestine. Oxalates spermidine/spermine N1-acetyl transferase 1 Mus musculus
4 Previously, calcium oxalate kidney stone formation by the SAT-1-knockout mouse generated the hypothesis that SAT-1 has a major role in oxalate excretion via the intestine. Oxalates spermidine/spermine N1-acetyl transferase 1 Mus musculus