Pub. Date : 2018 Nov 30
PMID : 30376995
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we show that cold-sensitive receptor TRPM8 is activated by pro-oxidant tert-butyl hydroperoxide (tBHP). | tert-Butylhydroperoxide | transient receptor potential cation channel, subfamily M, member 8 | Rattus norvegicus |
| 2 | In this study, we show that cold-sensitive receptor TRPM8 is activated by pro-oxidant tert-butyl hydroperoxide (tBHP). | tert-Butylhydroperoxide | transient receptor potential cation channel, subfamily M, member 8 | Rattus norvegicus |
| 3 | WS-12, a selective TRPM8 channel agonist, and tBHP increased intracellular Ca2+ concentration in differentiated PC12 cells; an effect attenuated by AMTB, a selective TRPM8 channel blocker, and siRNA-mediated TRPM8 knockdown. | tert-Butylhydroperoxide | transient receptor potential cation channel, subfamily M, member 8 | Rattus norvegicus |
| 4 | WS-12, a selective TRPM8 channel agonist, and tBHP increased intracellular Ca2+ concentration in differentiated PC12 cells; an effect attenuated by AMTB, a selective TRPM8 channel blocker, and siRNA-mediated TRPM8 knockdown. | tert-Butylhydroperoxide | transient receptor potential cation channel, subfamily M, member 8 | Rattus norvegicus |
| 5 | Blockade of TRPM8 channels also reduced WS-12- and tBHP-evoked norepinephrine secretion from the cells. | tert-Butylhydroperoxide | transient receptor potential cation channel, subfamily M, member 8 | Rattus norvegicus |