Title : Rapid liquid chromatography tandem mass-spectrometry screening method for urinary metabolites of primary hyperoxaluria.

Pub. Date : 2019 Mar

PMID : 30373392






2 Functional Relationships(s)
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1 Clinical assessment confirmed that mean urinary glycolate, glycerate and 2,4-dihydroxyglutarate excretion were significantly elevated in patients with PH1, PH2 and PH3, respectively. glycolic acid polyhomeotic homolog 2 Homo sapiens
2 The greatest sensitivity and specificity for PH1, PH2 and PH3 was achieved at cut-offs of 193, 100 and 4.9 mumol/mmol for glycolate, glycerate and 2,4-dihydroxyglutarate, respectively. glycolic acid polyhomeotic homolog 2 Homo sapiens