Pub. Date : 2019
PMID : 30370860
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We also observed that both compounds up-regulated the p53 expression where Emodin causes nuclear p53 localization, which leads to down-regulation in mTOR expression and induces autophagy while Chrysophanol inhibits p53 translocation into nucleus, up-regulates mTOR expression and inhibits autophagy. | Emodin | tumor protein p53 | Homo sapiens |
2 | We also observed that both compounds up-regulated the p53 expression where Emodin causes nuclear p53 localization, which leads to down-regulation in mTOR expression and induces autophagy while Chrysophanol inhibits p53 translocation into nucleus, up-regulates mTOR expression and inhibits autophagy. | Emodin | tumor protein p53 | Homo sapiens |
3 | We also observed that both compounds up-regulated the p53 expression where Emodin causes nuclear p53 localization, which leads to down-regulation in mTOR expression and induces autophagy while Chrysophanol inhibits p53 translocation into nucleus, up-regulates mTOR expression and inhibits autophagy. | Emodin | tumor protein p53 | Homo sapiens |