Title : In-silico identification of small molecules targeting H-Ras and in-vitro cytotoxicity with caspase-mediated apoptosis in carcinoma cells.

Pub. Date : 2019 Apr

PMID : 30367521






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 H-Ras oncogene plays a critical role in the transformation of normal cells to a malignant phenotype through constitutive activation of the GTP bound protein leading to uncontrolled cell proliferation in several human cancers. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens