Title : Chemotherapy in pregnancy: exploratory study of the effects of paclitaxel on the expression of placental drug transporters.

Pub. Date : 2019 Oct

PMID : 30367323






1 Functional Relationships(s)
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1 Results In the in vitro model, the expression of twelve drug-transporters genes was found to be significantly down-regulated after exposure to paclitaxel, including ABCC10, SLC28A3, SLC29A2, and ATP7B (involved in the transport of taxanes, antimetabolites, and cisplatin, respectively). Cisplatin ATP binding cassette subfamily C member 10 Homo sapiens