Pub. Date : 2018 Oct
PMID : 30355102
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, oxygen and glucose deprivation promoted MDM2 binding with p53 in neurons. | Oxygen | tumor protein p53 | Homo sapiens |
| 2 | Disruption of the MDM2-p53 interaction with nutlin-3a, or MDM2 knockdown by siRNA, triggered p53 accumulation, which increased neuronal susceptibility to oxygen and glucose deprivation-induced apoptosis. | Oxygen | tumor protein p53 | Homo sapiens |
| 3 | Disruption of the MDM2-p53 interaction with nutlin-3a, or MDM2 knockdown by siRNA, triggered p53 accumulation, which increased neuronal susceptibility to oxygen and glucose deprivation-induced apoptosis. | Oxygen | tumor protein p53 | Homo sapiens |