Title : A Novel and Selective p38 Mitogen-Activated Protein Kinase Inhibitor Attenuates LPS-Induced Neuroinflammation in BV2 Microglia and a Mouse Model.

Pub. Date : 2018 Dec

PMID : 30327995

1 Functional Relationships(s)
Compound Name
Protein Name
1 Our results showed that NJK14047 markedly reduced the production of nitric oxide and prostaglandin E2 by downregulating the expression of various proinflammatory mediators such as nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-alpha and interleukin-1beta in LPS-induced BV2 microglia. Dinoprostone interleukin 1 beta Mus musculus