Title : Chromosomal instability causes sensitivity to protein folding stress and ATP depletion.

Pub. Date : 2018 Oct 16

PMID : 30327366






3 Functional Relationships(s)
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1 PARP activation causes depletion of its substrate, nicotinamide adenine dinucleotide (NAD+) and subsequent loss of Adenosine Tri-Phosphate (ATP), and we found that adding ATP or nicotinamide (a precursor in the synthesis of NAD+) could rescue the observed phenotypes. NAD Poly-(ADP-ribose) polymerase Drosophila melanogaster
2 PARP activation causes depletion of its substrate, nicotinamide adenine dinucleotide (NAD+) and subsequent loss of Adenosine Tri-Phosphate (ATP), and we found that adding ATP or nicotinamide (a precursor in the synthesis of NAD+) could rescue the observed phenotypes. NAD Poly-(ADP-ribose) polymerase Drosophila melanogaster
3 PARP activation causes depletion of its substrate, nicotinamide adenine dinucleotide (NAD+) and subsequent loss of Adenosine Tri-Phosphate (ATP), and we found that adding ATP or nicotinamide (a precursor in the synthesis of NAD+) could rescue the observed phenotypes. NAD Poly-(ADP-ribose) polymerase Drosophila melanogaster