Title : Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade.

Pub. Date : 2019 Feb

PMID : 30315349






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Myeloid-derived suppressor cells (MDSCs) are immature monocytes and granulocytes that impede immune-mediated clearance of malignant cells by multiple mechanisms, including the formation of immunosuppressive reactive oxygen species (ROS) via the myeloid cell NADPH oxidase (NOX2). Reactive Oxygen Species cytochrome b-245, beta polypeptide Mus musculus
2 Myeloid-derived suppressor cells (MDSCs) are immature monocytes and granulocytes that impede immune-mediated clearance of malignant cells by multiple mechanisms, including the formation of immunosuppressive reactive oxygen species (ROS) via the myeloid cell NADPH oxidase (NOX2). Reactive Oxygen Species cytochrome b-245, beta polypeptide Mus musculus