Pub. Date : 2019 Jul
PMID : 30315250
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway. | tubeimoside I | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In three human breast cancer cell lines, we demonstrated that Akt-mTOR-eEF-2K pathway was involved in TBMS1-induced activation of autophagy, while Akt-mediated downregulations of Mcl-1, Bcl-xl, and Bcl-2 led to the activation of apoptosis of the breast cancer cells. | tubeimoside I | AKT serine/threonine kinase 1 | Homo sapiens |