Title : Transfection of the CD8 gene enhances T-cell recognition.

Pub. Date : 1987 Apr 2-8

PMID : 3031507






2 Functional Relationships(s)
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1 In previous experiments we have introduced the T-cell receptor alpha- and beta-chain genes from a CD8-positive cytolytic T cell specific for the antigen fluorescein (FL) and the H-2D molecule of the major histocompatibility complex (MHC) into a CD8-negative recipient cell. Fluorescein CD8a molecule Homo sapiens
2 Here we show that recognition of FL-conjugated lymphoblasts by the transfectant is enhanced by supertransfecting it with the CD8 gene. Fluorescein CD8a molecule Homo sapiens