Pub. Date : 2018 Sep
PMID : 30309416
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: (1) In vivo experiment: compared with the corresponding PBS control group, the expressions of the positive-associated proteins ATG5, ATG7 and LC3-II in liver tissue of the APAP intervention group were down-regulated in the wild-type and GLT25D2-/- mice, while the expression of the negative correlation protein P62 was up-regulated, indicating that the overall level of autophagy decreased after treatment with APAP. | 4-amino-N-acetyl-N-methylaniline | microtubule-associated protein 1 light chain 3 alpha | Mus musculus |
| 2 | Fluorescence microscopy showed that GFP-LC3 positive cells in both wild-type and GLT25D2-/- mice hepatocytes were significantly increased after APAP intervention as compared with those of PBS control group, and the proportion of GFP-LC3 positive cells in GLT25D2-/- mice was significantly higher than that in wild-type mice (0.64+-0.08 vs. 0.36+-0.05, P > 0.05). | 4-amino-N-acetyl-N-methylaniline | microtubule-associated protein 1 light chain 3 alpha | Mus musculus |
| 3 | Fluorescence microscopy showed that GFP-LC3 positive cells in both wild-type and GLT25D2-/- mice hepatocytes were significantly increased after APAP intervention as compared with those of PBS control group, and the proportion of GFP-LC3 positive cells in GLT25D2-/- mice was significantly higher than that in wild-type mice (0.64+-0.08 vs. 0.36+-0.05, P > 0.05). | 4-amino-N-acetyl-N-methylaniline | microtubule-associated protein 1 light chain 3 alpha | Mus musculus |