Title : The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1.

Pub. Date : 2018 Oct 23

PMID : 30305425






1 Functional Relationships(s)
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1 We crystallized cladribine-TP, clofarabine-TP, fludarabine-TP, vidarabine-TP, cytarabine-TP, and gemcitabine-TP in the catalytic pocket of SAMHD1. fludarabine-tp SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens