Title : Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2α.

Pub. Date : 2018 Dec 4

PMID : 30293811






1 Functional Relationships(s)
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1 Here we report the crystal structure of the C2 domain of PI3K-C2alpha in complex with the phosphoinositide head-group mimic inositol hexaphosphate, revealing two distinct pockets for membrane binding. Phytic Acid phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Homo sapiens