Title : Potential Role for Osteocalcin in the Development of Atherosclerosis and Blood Vessel Disease.

Pub. Date : 2018 Oct 4

PMID : 30287742






1 Functional Relationships(s)
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1 The current literature suggests that undercarboxylated osteocalcin stimulates the phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) signaling pathway to upregulate nitric oxide and nuclear factor kappa beta (NF-kbeta) in vascular cells, possibly protecting endothelial function and preventing atherogenesis. Nitric Oxide AKT serine/threonine kinase 1 Homo sapiens