Title : Celastrol Reverses Palmitic Acid-Induced Insulin Resistance in HepG2 Cells via Restoring the miR-223 and GLUT4 Pathway.

Pub. Date : 2019 Apr

PMID : 30287053






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Celastrol Reverses Palmitic Acid-Induced Insulin Resistance in HepG2 Cells via Restoring the miR-223 and GLUT4 Pathway. celastrol microRNA 223 Homo sapiens
2 Moreover, knocking down miR-223 abolished celastrol"s anti-IR effects in the PA-induced model. celastrol microRNA 223 Homo sapiens
3 CONCLUSIONS: Collectively, our results demonstrated that celastrol reverses PA-induced IR-related alterations, in part via miR-223 in HepG2 cells. celastrol microRNA 223 Homo sapiens