Title : Effect of celastrol on the progression of polycystic kidney disease in a Pkd1-deficient mouse model.

Pub. Date : 2018 Nov 1

PMID : 30268856






1 Functional Relationships(s)
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1 Moreover, celastrol reduced the renal mRNA expression levels of tumor necrosis factor-alpha, interleukin-1beta, P2RX7, F4/80, CD68, transforming growth factor-beta, collagen-1, and fibronectin, which were high in the Pkd1 miR TG mice. celastrol interleukin 1 beta Mus musculus