Title : A single synonymous mutation determines the phosphorylation and stability of the nascent protein.

Pub. Date : 2019 Mar 1

PMID : 30252118






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Here we show that the binding of MDM2 to the p53 mRNA brings ATM to the p53 polysome where it phosphorylates the nascent p53 at serine 15 and prevents MDM2-mediated degradation of p53. Serine tumor protein p53 Homo sapiens
2 Here we show that the binding of MDM2 to the p53 mRNA brings ATM to the p53 polysome where it phosphorylates the nascent p53 at serine 15 and prevents MDM2-mediated degradation of p53. Serine tumor protein p53 Homo sapiens
3 Here we show that the binding of MDM2 to the p53 mRNA brings ATM to the p53 polysome where it phosphorylates the nascent p53 at serine 15 and prevents MDM2-mediated degradation of p53. Serine tumor protein p53 Homo sapiens
4 Here we show that the binding of MDM2 to the p53 mRNA brings ATM to the p53 polysome where it phosphorylates the nascent p53 at serine 15 and prevents MDM2-mediated degradation of p53. Serine tumor protein p53 Homo sapiens