Title : Metformin inhibits IgE- and aryl hydrocarbon receptor-mediated mast cell activation in vitro and in vivo.

Pub. Date : 2018 Dec

PMID : 30242842






1 Functional Relationships(s)
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1 Using AhR reporter cells, Huh7-DRE-Luc cells, a human mast cell line, HMC-1, and BMMCs, metformin"s inhibitory effect was mediated through the suppression of FICZ-induced AhR activity, calcium mobilization and ROS generation. Metformin MIR7-3 host gene Homo sapiens