Title : Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin.

Pub. Date : 2018 Dec 7

PMID : 30240970






6 Functional Relationships(s)
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1 Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin. Melatonin H19 imprinted maternally expressed transcript Homo sapiens
2 Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin. Melatonin H19 imprinted maternally expressed transcript Homo sapiens
3 The aim of this study was to characterize the therapeutic role of melatonin as well as the underlying molecular mechanism (its effects on the expression of H19 and its downstream signaling pathways) in the treatment of PAH. Melatonin H19 imprinted maternally expressed transcript Homo sapiens
4 Finally, melatonin treatment inhibited cell proliferation; upregulated the expression of H19, miR-675-3p, and PDCD4; and downregulated the expression of miR-200a and IGF1R. Melatonin H19 imprinted maternally expressed transcript Homo sapiens
5 This study demonstrated the role of H19-miR-675-3p-IGF1R- and H19-miR-200a-PDCD4-signaling pathways in the melatonin treatment of PAH. Melatonin H19 imprinted maternally expressed transcript Homo sapiens
6 This study demonstrated the role of H19-miR-675-3p-IGF1R- and H19-miR-200a-PDCD4-signaling pathways in the melatonin treatment of PAH. Melatonin H19 imprinted maternally expressed transcript Homo sapiens