Title : Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer.

Pub. Date : 2018

PMID : 30228938






1 Functional Relationships(s)
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1 Our study suggests that targeting the CCL2/CCR2 chemokine axis decreases TAM at the metastatic site, disrupting the immunosuppressive TME and rendering mCRC susceptible to anti-tumor T-cell responses. tam C-C motif chemokine ligand 2 Homo sapiens