Pub. Date : 2018 Oct 12
PMID : 30224059
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ca2+-dependent inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate. | Thiamine Pyrophosphate | branched chain keto acid dehydrogenase kinase | Homo sapiens |
| 2 | Thiamine pyrophosphate (TPP) is required as a coenzyme for the E1 component of the BCKDH complex and can also bring about activation of the complex by inhibiting BDK. | Thiamine Pyrophosphate | branched chain keto acid dehydrogenase kinase | Homo sapiens |
| 3 | Thiamine pyrophosphate (TPP) is required as a coenzyme for the E1 component of the BCKDH complex and can also bring about activation of the complex by inhibiting BDK. | Thiamine Pyrophosphate | branched chain keto acid dehydrogenase kinase | Homo sapiens |
| 4 | The present study shows that free Ca2+ in the physiological range greatly increases the sensitivity of BDK to inhibition by TPP (IC50 of 2.5 muM in the presence of 1 muM free Ca2+). | Thiamine Pyrophosphate | branched chain keto acid dehydrogenase kinase | Homo sapiens |