Pub. Date : 2018 Sep 20
PMID : 30220454
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We now show that caspase-2, whose expression is ER-stress inducible and elevated in human and mouse NASH, controls the buildup of hepatic-free cholesterol and triglycerides by activating sterol regulatory element-binding proteins (SREBP) in a manner refractory to feedback inhibition. | Triglycerides | caspase 2 | Homo sapiens |