Title : Targeting HMGB1/TLR4 axis and miR-21 by rosuvastatin: role in alleviating cholestatic liver injury in a rat model of bile duct ligation.

Pub. Date : 2019 Jan

PMID : 30203151






3 Functional Relationships(s)
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1 Targeting HMGB1/TLR4 axis and miR-21 by rosuvastatin: role in alleviating cholestatic liver injury in a rat model of bile duct ligation. Rosuvastatin Calcium microRNA 21 Rattus norvegicus
2 Furthermore, Rvs-treated group showed a significant reduction in the expression of miR-21 in comparison to the untreated group. Rosuvastatin Calcium microRNA 21 Rattus norvegicus
3 Accordingly, rosuvastatin interference with the HMGB1/TLR4 and miR-21 expression could explain its hepatoprotective effect in cholestatic liver injury. Rosuvastatin Calcium microRNA 21 Rattus norvegicus