Pub. Date : 2018 Sep
PMID : 30186748
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nuclear accumulation of HSF1 and Nrf2 transcription factors was detected upon both arsenite and MG132 treatment, while HSF2 nuclear levels increased in MG132-treated cells. | arsenite | heat shock transcription factor 1 | Homo sapiens |
| 2 | Critically, HSF1-mediated UBC trans-activation upon arsenite exposure relies on transcription factor binding to previously mapped distal HSEs, as demonstrated to occur under proteasome inhibition. | arsenite | heat shock transcription factor 1 | Homo sapiens |