Title : Adenosine Receptor-Mediated Developmental Loss of Spike Timing-Dependent Depression in the Hippocampus.

Pub. Date : 2019 Jul 22

PMID : 30169759






1 Functional Relationships(s)
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1 We were interested in the mechanisms underlying this maturation related loss of t-LTD and we found that at CA3-CA1 synapses, presynaptic NMDA receptors (pre-NMDARs) are tonically active between P13 and P21, mediating an increase in glutamate release during this critical period of plasticity. Glutamic Acid carbonic anhydrase 3 Mus musculus