Title : Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation.

Pub. Date : 2018 Aug 30

PMID : 30166529






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NMNAT1 is a nuclear enzyme essential for nicotinamide adenine dinucleotide (NAD) biosynthesis pathways, but the mechanisms underlying the LCA pathology and whether NMNAT1 has a role in normal retinal development remain unclear. NAD nicotinamide nucleotide adenylyltransferase 1 Homo sapiens
2 NMNAT1 is a nuclear enzyme essential for nicotinamide adenine dinucleotide (NAD) biosynthesis pathways, but the mechanisms underlying the LCA pathology and whether NMNAT1 has a role in normal retinal development remain unclear. NAD nicotinamide nucleotide adenylyltransferase 1 Homo sapiens
3 Decreased intracellular NAD content was observed and the addition of NAD to the culture medium attenuated sh-Nmnat1-induced apoptosis. NAD nicotinamide nucleotide adenylyltransferase 1 Homo sapiens