Title : Microvascular Endothelial Dysfunction in Human Obesity: Role of TNF-α.

Pub. Date : 2019 Feb 1

PMID : 30165404






1 Functional Relationships(s)
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1 TNF-alpha, generated either in small vessels or within the perivascular adipose tissue (PVAT) of patients with obesity, stimulates reactive oxygen species generation, mainly through NAD(P)H oxidase activation, which in turn reduces nitric oxide (NO) availability. oxygen species tumor necrosis factor Homo sapiens