Pub. Date : 1986 Sep
PMID : 3016022
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using cytoplasmic dot blot hybridization, IGF-I inhibited the levels of human GH mRNA sequences in these cells and also prevented the GHRH-induced stimulation of GH mRNA. | ghrh | insulin like growth factor 1 | Homo sapiens |
| 2 | A monoclonal antibody to the type I IGF-I receptor (alpha IR3) prevented the inhibitory effects of IGF-I on basal and GHRH-stimulated GH secretion. | ghrh | insulin like growth factor 1 | Homo sapiens |
| 3 | A monoclonal antibody to the type I IGF-I receptor (alpha IR3) prevented the inhibitory effects of IGF-I on basal and GHRH-stimulated GH secretion. | ghrh | insulin like growth factor 1 | Homo sapiens |
| 4 | Thus, IGF-I suppresses basal and GHRH-stimulated GH secretion and GH mRNA levels in pituitary adenoma cells, indicating that IGF-I acts selectively on the somatotroph to directly regulate GH gene expression. | ghrh | insulin like growth factor 1 | Homo sapiens |
| 5 | Thus, IGF-I suppresses basal and GHRH-stimulated GH secretion and GH mRNA levels in pituitary adenoma cells, indicating that IGF-I acts selectively on the somatotroph to directly regulate GH gene expression. | ghrh | insulin like growth factor 1 | Homo sapiens |