Title : isoDGR-Peptides for Integrin Targeting: Is the Time Up for RGD?

Pub. Date : 2018 Sep 13

PMID : 30152697






1 Functional Relationships(s)
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1 The peptide sequence Arg-Gly-Asp (RGD), which is present in a number of endogenous integrin ligands like fibronectin, vitronectin, and related proteins of the extracellular matrix (ECM), has been extensively used as a targeting vector for therapeutic as well as diagnostic purposes, and cilengitide, a cyclic RGD peptide, has entered clinical trials for the treatment of various cancers. Glycine vitronectin Homo sapiens