Title : Study of glucocorticoid receptors in T lymphocytes (CD3/GCR) as predictor of steroid responsiveness in Egyptian children with idiopathic nephrotic syndrome.

Pub. Date : 2018 Jul-Aug

PMID : 30152427






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1 Study of glucocorticoid receptors in T lymphocytes (CD3/GCR) as predictor of steroid responsiveness in Egyptian children with idiopathic nephrotic syndrome. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
2 Study of glucocorticoid receptors in T lymphocytes (CD3/GCR) as predictor of steroid responsiveness in Egyptian children with idiopathic nephrotic syndrome. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
3 Our objective was to determine the relation between steroid responsiveness and GCR expression in T lymphocytes. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
4 GCR/CD3% was significantly lower in LR group in comparison with ER and control groups, with a significant negative correlation between time of steroid responsiveness and GCR/CD3%. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
5 LR group showed lower GCR expression in T lymphocytes before starting therapy which may mean that GCR expression could be part of a pathophysiological mechanism of steroid responsiveness in these children and can be used as a useful diagnostic marker to predict steroid responsiveness in patients with INS. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
6 LR group showed lower GCR expression in T lymphocytes before starting therapy which may mean that GCR expression could be part of a pathophysiological mechanism of steroid responsiveness in these children and can be used as a useful diagnostic marker to predict steroid responsiveness in patients with INS. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens