Title : Neurokinin-1 receptor (NK1R) inhibition sensitizes APL cells to anti-tumor effect of arsenic trioxide via restriction of NF-κB axis: Shedding new light on resistance to Aprepitant.

Pub. Date : 2018 Oct

PMID : 30145367






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The stimulatory effect of NK1R inhibition on ATO cytotoxicity is probably mediated through up-regulation of p73, which can subsequently engage p21 and NF-kappaB pathway via transcriptional suppression of c-Myc. ato MYC proto-oncogene, bHLH transcription factor Homo sapiens