Title : STK405759 as a combination therapy with bortezomib or dexamethasone, in in vitro and in vivo multiple myeloma models.

Pub. Date : 2018 Jul 31

PMID : 30140376






1 Functional Relationships(s)
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1 STK405759 combined with dexamethasone or bortezomib had synergistic cytotoxic activity in RPMIS, CAG and MM1.S human MM cell lines through activation of caspase 2, 3, 8, 9 and PARP. Bortezomib caspase 2 Homo sapiens