Title : Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246.

Pub. Date : 2018 Aug 23

PMID : 30140002






1 Functional Relationships(s)
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1 The inhibition of Trx1 and Grx1 by APR-246/MQ is reversible and the inhibitory efficiency is dependent on the presence of glutathione. Glutathione thioredoxin Homo sapiens