Title : Role of PKB/SGK-dependent phosphorylation of GSK-3α/β in vascular calcification during cholecalciferol overload in mice.

Pub. Date : 2018 Sep 10

PMID : 30119888






1 Functional Relationships(s)
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1 In gsk-3WT mice, high-dosed cholecalciferol induced vascular calcification and aortic osteo-/chondrogenic signaling, shown by increased expression of osteogenic markers Msx2, Cbfa1 and tissue-nonspecific alkaline phosphatase (Alpl). Cholecalciferol alkaline phosphatase, liver/bone/kidney Mus musculus