Title : Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease.

Pub. Date : 2018 Feb 1

PMID : 30108930






1 Functional Relationships(s)
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1 The compounds possessing the propargylamine moiety showed good MAO-B inhibitory activity with 6 and 8 portraying IC50 values between 14-20 fold better than ladostigil. (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate monoamine oxidase B Homo sapiens