Pub. Date : 2018 Oct 3
PMID : 30108130
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we show that following bursts of afferent activity, the neuromodulator and satiety peptide cholecystokinin (CCK) shifts the plasticity of GABA synapses in the dorsomedial nucleus of the hypothalamus of male Sprague Dawley rats from long-term depression to long-term potentiation (LTP). | gamma-Aminobutyric Acid | cholecystokinin | Rattus norvegicus |
| 2 | Here we show that following bursts of afferent activity, the neuromodulator and satiety peptide cholecystokinin (CCK) shifts the plasticity of GABA synapses in the dorsomedial nucleus of the hypothalamus of male Sprague Dawley rats from long-term depression to long-term potentiation (LTP). | gamma-Aminobutyric Acid | cholecystokinin | Rattus norvegicus |
| 3 | The current data provide novel evidence that cholecystokinin shifts the plasticity from long-term depression to long-term potentiation at GABA synapses in the rat dorsomedial nucleus of the hypothalamus. | gamma-Aminobutyric Acid | cholecystokinin | Rattus norvegicus |
| 4 | We also demonstrate that this plasticity requires the concerted action of cholecystokinin and glutamate on astrocytes, triggering the release of the gliotransmitter ATP, which subsequently increases GABA release from neighboring inhibitory terminals. | gamma-Aminobutyric Acid | cholecystokinin | Rattus norvegicus |