Pub. Date : 2018 Oct 1
PMID : 30098983
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
4 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
5 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
6 | Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by hydrolysis of the carbamoyl enzyme. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
7 | Therefore, carbamates are effective AChE inhibitors that have been developed as insecticides and as therapeutic agents. | Carbamates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |