Title : Identification of an Orally Bioavailable Chromene-Based Selective Estrogen Receptor Degrader (SERD) That Demonstrates Robust Activity in a Model of Tamoxifen-Resistant Breast Cancer.

Pub. Date : 2018 Sep 13

PMID : 30086626






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Fulvestrant is a steroid-based, selective estrogen receptor degrader (SERD) that both antagonizes and degrades ER-alpha and shows some activity in patients who have progressed on antihormonal agents. Steroids estrogen receptor 1 Homo sapiens
2 Fulvestrant is a steroid-based, selective estrogen receptor degrader (SERD) that both antagonizes and degrades ER-alpha and shows some activity in patients who have progressed on antihormonal agents. Steroids estrogen receptor 1 Homo sapiens