Title : Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.

Pub. Date : 2018 Sep

PMID : 30082863






1 Functional Relationships(s)
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1 In animal models, a single oral dose of a CutC/D inhibitor significantly reduced plasma TMAO levels for up to 3 d and rescued diet-induced enhanced platelet responsiveness and thrombus formation, without observable toxicity or increased bleeding risk. trimethyloxamine cutC copper transporter Homo sapiens