CPRiL

4 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	While inhibition of p38 activation using SB203580 did not affect TGFbeta-induced Notch3 expression, inhibition of ERK activation with a MEK1 inhibitor PD98059 dramatically reduced the event.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	mitogen-activated protein kinase kinase 1	Homo sapiens
2	Furthermore, enforced ERK activation through overexpression of the constitutively active MEK1 mutant MEK1Q56P upregulated Notch3 expression in HK-2 cells, and PD98059 reduced ERK activation and Notch3 expression in HK-2 cells expressing MEK1Q56P.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	mitogen-activated protein kinase kinase 1	Homo sapiens
3	Furthermore, enforced ERK activation through overexpression of the constitutively active MEK1 mutant MEK1Q56P upregulated Notch3 expression in HK-2 cells, and PD98059 reduced ERK activation and Notch3 expression in HK-2 cells expressing MEK1Q56P.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	mitogen-activated protein kinase kinase 1	Homo sapiens
4	Furthermore, enforced ERK activation through overexpression of the constitutively active MEK1 mutant MEK1Q56P upregulated Notch3 expression in HK-2 cells, and PD98059 reduced ERK activation and Notch3 expression in HK-2 cells expressing MEK1Q56P.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	mitogen-activated protein kinase kinase 1	Homo sapiens